What you need to know about the anti-Covid vaccine in the event of an underlying pathology

(partner content) People with certain underlying diseases or taking medication regularly can under certain conditions receive a vaccine against Covid-19. Update with Samitivej Hospital

According to the World Health Organization (WHO), if the anti-Covid-19 vaccine effectively strengthens immunity against the disease, it remains important to maintain barrier gestures such as wearing a face mask, washing hands regularly, maintain physical distance between people and avoid crowded areas.

This is because getting the vaccine is not a 100% guarantee that you will not contract Covid-19 from droplets projected by infected people coughing or sneezing around you, or by contact with their sputum, their saliva and phlegm, for example.

People with underlying medical conditions or those with regular medication needs should follow these basic tips:

The Covid-19 vaccine and people with underlying health conditions

State Tips

Coronary disease

The vaccine can be inoculated except in case of acute symptoms, unstable state of health or other symptoms that may endanger the patient. In this type of case, it is up to the patient's doctor to determine whether or not the patient is ready to receive the vaccine.

Chronic kidney disease requiring dialysis treatment

The vaccine can be inoculated except in case of acute symptoms, unstable state of health or other symptoms that may endanger the patient. In such cases, it is up to the patient's physician to determine whether or not the patient is ready to receive the vaccine.

Patients who have undergone an organ transplant

It is recommended to wait at least one month after surgery and to ensure that the condition is deemed stable by the doctor before the vaccine can be administered.

Chronic Obstructive Pulmonary Disease / Asthma

The vaccine can be inoculated except in case of acute symptoms or unstable state of health. In such cases, it is recommended to wait 2 to 4 weeks after the improvement of symptoms before the vaccine can be administered.

Ce qu'il faut savoir sur le vaccin anti-Covid en cas de pathologie sous-jacente

Cancer

The vaccine can be inoculated, except in the following circumstances:

People who are undergoing chemotherapy or are about to undergo cancer surgery should consult their doctor before receiving the vaccine.

Patients with blood cancers who have received a bone marrow transplant must wait 3 months before receiving the vaccine.

Diabetes and obesity

(People weighing more than 100 kg or having a BMI greater than 35/m2)

The vaccine can be inoculated except in case of acute symptoms or unstable state of health.

AIDS

The vaccine can be inoculated except in cases where the infectious disease has just been contracted and therefore requires careful and careful management.

Rheumatoid arthritis and autoimmune diseases

The vaccine can be administered except in case of acute symptoms or if the state of health is unstable.

Immune neuropathy disorders, such as: autoimmune encephalitis, multiple sclerosis, neuromyelitis optica, acute polyneuropathy, Guillain-Barré syndrome, chronic polyneuropathy, myelitis, myositis, Bell's palsy, and cranial neuritis.

The vaccine can be administered except in case of acute symptoms or when the state of health is unstable. In such cases, it is recommended to wait 4 weeks after the improvement of symptoms before the vaccine can be administered.

Cerebrovascular disease

The vaccine can be inoculated except in unstable cases or when the symptoms may present a danger. In such cases, it is up to the patient's physician to determine whether or not the patient is ready to receive the vaccine.

Epilepsy

There are no restrictions regarding the injection of a vaccine.

Other neurological disorders, such as: Parkinson's disease, dementia, motor neuron disease and genetic or age-related musculoskeletal disorders and neuropathy.

There are no restrictions regarding the injection of a vaccine.

COVID-19 Vaccination Recommendations for Patients Taking Medications Regularly or Taking Medications for Certain Underlying Conditions

Medication Recommendation
Corticosteroids

(Prednisolone 20 mg; equivalent of Dexamethasone 3 mg and Methylprednisolone 16 mg)

For a daily dose of 20 mg of Prednisolone or other corticosteroids at an equivalent dose, vaccination can be carried out without the need to stop the medication.

For a dosage of more than 20 mg per day, or if the patient is in the process of reducing the dosage of the drug, the patient must have stable symptoms before receiving the vaccine.

Immunosuppressants such as: azathioprine, IVIG and oral Cyclophosphamide

Vaccination can be carried out without the need to stop the medication.

Intravenous cyclophosphamide

The vaccine can be given if the symptoms are stable, with a recommendation to stop taking the drug for 1 week after the injection.

Mycophenolate

The vaccine can be given if the symptoms are stable, with a recommendation to stop taking the drug for 1 week after the injection.

methotrexate

The vaccine can be given if the symptoms are stable, with a recommendation to stop taking the drug for 1 week after the injection.

Hydroxychloroquine, Sulfasalazine, Leflunomide

There is no need to adjust the dosage or postpone the vaccination.

anticoagulant warfarin

The vaccine can be administered to patients with an INR less than 4, using a 25G or 27G syringe, and the muscle should not be kneaded after vaccination. After vaccination, the injection site should be gently pressed for 2-5 minutes to ensure that there is no further bleeding.

Antithrombotic agents, such as fondaparinux

Vaccination can be done, but it must be done before the injection of this type of medicine.

Non-vitamin K antagonist (NOAC) oral anticoagulants, such as Dabigatran, Rivaroxaban, Apixaban, and Edoxaban

Vaccination can be performed, but a 25 G or smaller syringe should be used and the muscle should not be kneaded after injection. As soon as the vaccination is done, gently compress the injection site for 2 to 5 minutes to ensure that there is no more possible bleeding.

Antiplatelet drugs, such as aspirin, clopidogrel, colostazol, ticagrelor, or prasugrel

Vaccination can be performed, but a 25 G or smaller syringe should be used and the muscle should not be kneaded after injection. As soon as the vaccination is done, gently compress the injection site for 2 to 5 minutes to ensure that there is no more possible bleeding.

Antibodies (drugs ending in -mab)

Rituximab: It is recommended to perform the vaccination 14 days before the first dose of this medicine or 1 month after taking this medicine.

Omalizumab, Benralizumab, Dupilumab: it is recommended to carry out the vaccination 7 days before or after taking these drugs.

Text translated from the English article by Dr Payia Chantadisai, titled Essential Covid-19 vaccine information for patients with underlying health conditions requiring regular medication

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