COVVID vaccine: latest data on the risk of disruption of the menstrual cycle

Is any change really low compared to the natural variation of normal cycles?

Thus, many women have reported changes in their rules after vaccination against COVID-19 and evidence of this gap were combined.British experts today highlight new observational studies which provide reassuring data suggesting that any change remains low compared to the natural variation of normal cycles.

One of the main authors, Dr. Victoria Male, a reproductive health specialist at the Imperial College in London, sums up these latest conclusions:

A first analysis of the data of 3,959 participants having recorded at least 6 consecutive cycles on a monitoring of the menstrual cycle, of which 2,403 vaccinated participants concludes in contrast to previous studies that:

A second study questioned 5,688 participants in specific menstrual changes (such as unexpected intermenstrual bleeding or more important menstrual pain than normal) during the preceding cycles and according to each dose of vaccine.This study seems to reveal a very high level of variation in normal cycles, hitherto not taken into account:

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According to experts, these new data are rather reassuring: changes in the menstrual cycle occur after vaccination, they no longer seem questionable, but they are weak compared to natural variation and are quickly reversed.

Is it really totally reassuring?In practice, the authors "derive" it, seek to avoid-which is possible in the United Kingdom-a 2-file vaccination scheme during the same cycle.

The British health agency, the MHRA (Medicines and Healthcare Products Regulatory Agency) has just said, for its part, that current evidence does not corroborate the existence of a link between changes in menstrual cycles and COVID vaccination.The British agency's recommendation to women knowing these changes after vaccination is to be treated according to the usual clinical routes.

Finally, experts come back to more recent evidence suggesting that covid infection can reduce the number and quality of sperm, therefore induce effects on fertility.

"There is still a lot to learn," finally recognize the authors who nevertheless call for more urgent research: to determine if a group of women is particularly vulnerable and better define the extent and persistence of these changes.